Research interests

Host-oral bacterial interactions in periodontal pathogenesis

Publication

1. Ji-Young Joo, Gil Sun Cha, Jin Chung, Ju-Youn Lee, Sung-Jo Kim, Jeomil Choi. Peptide 19 of Porphyromonas gingivalis Heat Shock Protein is A Potent Inducer of Low-Density Lipoprotein Oxidation. Journal of Periodontology. 88(2):e58-64. 2017.

2. Mi Hee Park, So Yeon Jung, Hee Sam Na, Jin Chung. Porphyromonas ingivalis induces autophagy in THP-1-derived macrophages. Molecular Oral Microbiology. 32:48-59. 2017.  

3. Sung-Hee Jeong, Hee-Sam Na, Su-Hyeon Park, Yong-Woo Ahn, Jin Chung. Topical sulfasalazine for unresponsive oral lichen planus. Quintessence International. 47(4):319-327. 2016.

4. Seyeon Kim, Mi Hee Park, Yu Ri Song, Hee Sam Na, Jin Chung. Aggregatibacter actinomycetemcomitans-Induced AIM2 Inflammasome Activation Is Suppressed by Xylitol in Differentiated THP-1 Macrophages. Journal of Periodontology. 87(6):e116-126. 2016.

5. Hee Sam Na, Yu Ri Song, Seyeon Kim, Jun-Young Heo, Hae-Young Chung, Jin Chung. Aloin Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells. Journal of Periodontology. 87(6):e108-115. 2016.

6. Hee Sam Na, Mi Hee Park, Yu Ri Song, Seyeon Kim, Hyung-Joon Kim, Ju Youn Lee, Jeom-Il Choi, and Jin Chung. Elevated miR-128 in Periodontitis Mitigates Tumor Necrosis Factor-Alpha Response via P38 Signaling Pathway in Macrophages. Journal of Periodontology. 87(9):e173-182. 2016.

7. Mi Hee Park, Eunjoo Park, Hyung-Joon Kim, Hee Sam Na, Jin Chung. Porphyromonas gingivalis-induced miR-132 regulates TNFα expression in THP-1 derived macrophages. SpringerPlus. 5(1):761. 2016.

8. Eunjoo Park, Mi Hee Park, Hee Sam Na, Jin Chung. Xylitol induces cell death in lung cancer A549 cells by autophagy. Biotechnology Letters. 37(5):983-990. 2015.  

9. Ji Hee Hwang, Jin Chung, Hee-Sam Na, Eunjoo Park, Sangwon Kwak, Hyeon-Cheol Kim. Comparison of bacterial leakage resistance of various root canal filling materials and methods: Confocal laser-scanning microscope study. Scanning. 37(6):422-428. 2015.

10. Eunjoo Park, Hee Sam Na, Sheon Min Kim, Shannon Wallet, Seung hee Cha, and Jin Chung. Xylitol, an anti-caries agent, exhibits potent inhibition of inflammatory responses in human THP-1-derived macrophages infected with Porphyromonas gingivalis. Journal of Periodontology. 85(6): e2112-2223. 2014.

11. Eunjoo Park, Hee Sam Na, Yu-Ri Song, Seong Yeol Shin, You-Me Kim, and Jin Chung. Activation of NLRP3 and AIM2 Inflammasomes by Porphyromonas gingivalis Infection. Infection and Immunity. 82(1):112-123. 2014. 

12. Hee Sam Na, Eun J. Lim, So Yeon Jeong, Mi H. Ryu, Mi Hee Park, and Jin Chung. Plasminogen Activator Inhibitor Type 1 Expression Induced by Lipopolysaccharide of Porphyromonas gingivalis in Human Gingival Fibroblast. Journal of Microbiology. 52(2):154-160. 2014. 

13. Yeon Ja Choi, Hyung Suk Kim, Juyoun Lee, Jin Chung, Jun Sik Lee, Jae Sue Choi, Taek Rim Yoon, Hyung Keun Kim, Hae Young Chung.  Down-regulation of oxidative stress and COX-2 and iNOS expressions by dimethyl lithospermate in aged rat kidney. Archives of Pharmacal Research. 37(8):1032-1038. 2014. 

14. Hee Sam Na, Sheon Min Kim, Seyeon Kim, Yoon Hee Choi, Jin Chung. Effect of Xylitol on various Oral bacteria. International Journal of Oral Biology, 38(4):175-180. 2013.

15. Hee Sam Na, Seyeon Kim, Yoon Hee Choi, Ju-Yeon Lee, Jin Chung. Oral Microbiota Comparison between Healthy volunteers, Periodontitis patients and Oral cancer patients. International Journal of Oral Biology. 38(4):181-188. 2013.

16. Gyoo Cheon Kim, Hyun Wook Lee, June Ho Byun, Jin Chung, Young Chan Jeon and Jae Koo Le. Dental Applications of Low-Temperature Nonthermal Plasmas. Plasma Processes and Polymers. 10(3):199-206. 2013.

17. Sang-Jin Lee, Jin Chung, Hee-Sam Na, Eun-Joo Park, Hyo-Jin  Jeon, Hyeon-Cheol Kim. Characteristics of novel root-end filling material using epoxy resin and Portland cement. Clinical Oral Investigations. 17(3):1009-1015. 2013. 

18. Yoon Hee Choi, Jin Chung, Hee Sam Na. Molecular Methods for Studying the Human Microbiota. Journal of Bacteriology and Virology.  43(1):67-72. 2012.

19. Ji S. Kim, Kyung D. Kim, Hee S. Na, So Y. Jeong, Hae R. Park, Shin Kim, Jin Chung. TNF-a and IL-1b expression pathway induced by Streptococcus mutans in macrophage cellline Raw 264.7. Molecular Oral Microbiology. 27(3):149-159. 2012. 

20. Jin Chung, Young Hwa Lee, Jun Sik Lee, Tae kwun Ha, Myung Ho Jeong, Taek Rim Yoon, Hyung Keun Kim. Inulin induces dendritic cells apoptosis through the caspase-dependent pathway and mitochondrial dysfunction. Biological & Pharmaceutical Bulletin. 34(4):495-500. 2011.

21. Hwa Sun Lee, Hee Sam Na, So-Yeon Jeong, Sung-Hee Jeong, Hae-Ryoun Park, Jin Chung. Periodontopathogen LPSs regulate microRNA Expression in Human Gingival Epithelial Cells. International Journal of Oral Biology. 36(3):109-116. 2011. 

22. Lee YH, Na HS, Jeong SY, Jeong SH, Park HR, Chung J. Comparison of inflammatory microRNA expression in healthy and periodontitis tissues. Biocell. 35(2):43-49. 2011.

23. Juyoun Lee, Jin Chung, Ji Hyun Kim, Myung Ho Jeong, Taek Rim Yoon, Hyung Keun Kim, Identification of Gene Expression Profiles by Microarray and Confirmation of Gene Expression by RT-PCR during Osteoblastic Differentiation by BMP-2. Tissue Engineering and Regenerative Medicine. 7(2):155-162. 2010.

24. Mi Heon Ryu, Hyung Mok Park, Jin Chung, Chang Hun Lee, Hae Ryoun Park. Hypoxia-inducible factor-1alpha mediates oral squamous cell carcinoma invasion via upregulation of alpha5 integrin and fibronectin. Biochemical and Biophysical Research Communications  393(1):11-15. 2010.

25. Mi Heon Ryu, Jeong Hee Park, Ji Eun Park, Jin Chung, Chang Hun Lee, Hae Ryoun Park. Cobalt chloride stimulates phosphoinositide 3-kinase/Akt signaling through the epidermal growth factor receptor in oral squamous cell carcinoma. BIOCELL. 34(1):15-21. 2010.

26. Ho-Kyeong Jin, Young-Hwa Lee, So-Yeon Jeong, Hee-Sam Na, Hae-Ryoun Park, Jin Chung. Induction of Signal Transduction Pathway Genes in Dendritic Cells by Lipopolysaccharides from Porphyromonas gingivalis and Escherichia coli. International Journal of Oral Biology. 35(3):113-119. 2010.

27. Young-Hwa Lee, So-Yeon Jeong, Hee-Sam Na, Sung-Hee Jeong, Hae-Ryoun Park, Jin Chung. Comparison of Cytokine Gene Induction in RAW 264.7 Cells by Porphyromonas gingivalis and Escherichia coli Lipopolysaccharide. International Journal of Oral Biology. 35(3):121-128. 2010.

28. Jin Chung, Mun Jeoung Choi, So Yeon Jeong, Jong Suk Oh, Hyung Keun Kim. Chemokines gene expression of RAW 264.7 cells by Actinobacillus actinomycetemcomitans lipopolysaccharide using microarray and RT-PCR analysis. Molecules and Cells. 27(2):257-261. 2009.

29. MJ Kim, HI Kim, J Chung, TS Jeong, HR Park. (-)-Epigallocatechin-3-Gallate (EGCG) increases the viability of serum-starved A549 cells through its effect on Akt. The American Journal of Chinese Medicine. 37(4):723-734. 2009. 

30. Jin Chung, Hwa Sun Lee, Hae Young Chung, Taek Rim Yoon, Hyung Keun Kim. Salicylideneamino-2-thiophenol inhibits inflammatory mediator genes (RANTES, MCP-1, IL-8 and HIF-1alpha) expression induced by tert-butyl hydroperoxide via MAPK pathways in rat peritoneal macrophages. Biotechnology Letters. 30(9):1553-1558. 2008. 

31. Jae-Hyoun Park, Gyoo-Cheon Kim, Hyun-Ho Kwak, In-ryoung Kim, Seung-Eun Lee, Jin Chung, Hae-Ryoun Park, Sang-Hun Shin, Soo-Hyun Choi, Chul-Hoon Kim, Chang-Ok Nam, Bong-Soo Park. Chios Gum Mastic Induces Cell Cycle Arrest and Apoptosis in YD9 Human Oral Squamous Carcinoma Cells. The Korean Journal of Physical Anthropology. 21(1):55-68. 2008.

32. Hye-ock Jang, Ji-Suk Kim, Woo-Cheol Kwon, Jeong-Kuk Kim, Myung-Suk Ko, Dong-Hoo Kim, Won-Il Kim, Young-Chan Jeon, In-Kyo Chung, Sang-Hun Shin, Jin Chung, Moon-Kyung Bae, Il Yun. The Effect of Lead on Calcium Release Activated Calcium Influx in Primary Cultures of Human Osteoblast-like Cells. Arch Pharm Res. 31(2):188-194. 2008.

33. Hyung Keun Kim, Lee Hwa soon, Hae Ryoun Park, Jun Sik Lee, Hae Young Chung, Jin Chung. Down-regulation of iNOS and TNF-α expression by kaempferol via NF-κB inactivation in aged rat gingival tissues. Biogerontology. 8(4):399-408. 2007. 

34. Hyung Keun Kim, Hae Ryoun Park, Kyoung Hee Sul, Hae Young Chung, Jin Chung. Induction of RANTES and CCR5 through NF-kB activation via MAPK pathway in aged rat gingival tissues. Biotechnology Letters. 28:17-23. 2006.

35. Kang MS, Kim BG, Chung J, Lee HC, Oh JS. Inhibitory effect of Weissella cibaria isolates on the production of volatile sulphur compounds.  Journal of Clinical Periodontology. 33(3):226-232. 2006. 

36. MS Kang, J Chung, SM Kim, KH Yang, JS Oh. Effect of Weissella cibaria Isolates on the Formation of Streptococcus mutans Biofilm. Caries Research. 40:418-425. 2006. 

37. Han SJ, Jeong SY, Nam YJ, Yang KH, Lim HS, Chung J. Xylitol inhibits inflammatory cytokine expression induced by lipopolysaccharide from Porphyromonas gingivalis. Clinical and diagnostic laboratory immunology.  12(11):1285-1291. 2005.

38. Jin Chung, Dong-Hoon Lee, Tae-Sung Chung, Shin Kim, Jong-Suk Oh. Glucan production and gtf expression in the samples of caries-active and caries-free children. Journal of Bacteriology and Virology. 34(2)101-110. 2004.

39. J Chung, ES Ha, HR Park, S Kim. Isolation and characterization of Lactobacillus species inhibiting the formation of Stretpcoccus mutans biofilm. Oral Microbiology Immunology. 19:214-216. 2004.

40. Hyun-Jin Kim, Jin Chung. Streptococcus mutans gtfD 유전자 발현에 대한 당의 영향. International Journal of Oral Biology. 28(4):49-54. 2003. 

Books

Oral Biology: Molecular Techniques and Applications (1st edition/ Springer, 2010)